THE SERUM PROTEINS IN INFECTIOUS MONONUCLEOSIS. ELECTROPHORETIC STUDIES

The Serum Proteins in Infectious Mononucleosis

Previous investigations have shown the very frequent occurrence in infectious mononucleosis of abnormal findings on liver function tests (1-7), and of hepatic involvement on histologic examination of both autopsy (8-11) and biopsy material (1, 12-14) in cases with and without jaundice. Alterations observed in the composition of the serum proteins (2, 4, 6, 15, 16a) appear to be compatible with ...

Serological studies in infectious mononucleosis.

Serological investigations performed on 27 patients with illnesses resembling infectious mononucleosis showed a significant increase in high antibody titres (more than 1:40) to EB virus in 11 of the 12 who developed heterophile antibodies. Two of these patients, however, had a significant increase in antibody titre to cytomegalovirus and rubella virus, respectively. Of 15 patients who failed to...

A study of the Electrophoretic Pattern of the serum Proteins

Electrophoretic studies of the serum proteins in virus hepatitis.

The abnormal electrophoretic patterns of the serum proteins in the acute stage of virus hepatitis were first described by Gray and Barron in 1943 (1) and have since been confirmed by several investigators (2-5). In the last few years there has been considerable interest (6-13) in cases of hepatitis progressing to chronic liver disease, or developing post-necrotic cirrhosis. Except for the study...

Electrophoretic studies of the serum proteins in biliary cirrhosis.

Electrophoretic runs were performed with standard apparatus and technique, the experimental details having been reported previously (4). The buffer was sodium diethylbarbiturate (veronal) of pH 8.6 and ionic strength 0.1. In the estimation of the fractions as per cent of the serum proteins both ascending and descending patterns were used, the areas being divided by ordinates from the nadirs bet...